Suboxone Sublingual tablets

What is Suboxone and how is it used? Suboxone is a prescription opioid medicine used to block the effects of opioid medication, including pain relief, which can lead to opioid abuse. Suboxone may be used alone or with other medications. Suboxone belongs to a class of drugs called Opioid Antagonists, Analgesics, Opioid Partial Agonist. It is not known if Suboxone is safe and effective in children. What are the possible side effects of Suboxone? Suboxone may cause serious side effects including: weak or shallow breathing, breathing that stops during sleep, confusion, loss of coordination, extreme weakness, blurred vision, slurred speech, upper stomach pain, loss of appetite, dark urine, clay-colored stools, yellowing of the skin or eyes (jaundice), nausea, dizziness, worsening tiredness or weakness, shivering, goose bumps, increased sweating, feeling hot or cold, runny nose, watery eyes, diarrhea, and muscle pain Get medical help right away, if you have any of the symptoms listed above. The most common side effects of Suboxone include: dizziness, drowsiness, blurred vision, feeling drunk, trouble concentrating, withdrawal symptoms, tongue pain, redness or numbness inside your mouth, nausea, vomiting, constipation, headache, back pain, fast or pounding heartbeats, increased sweating, and sleep problems (insomnia) Tell the doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of Suboxone. For more information, ask your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. DESCRIPTION SUBOXONE sublingual tablet is an uncoated hexagonal orange tablet, debossed with an alphanumeric word identifying the product and strength. It contains buprenorphine HCl, a partial agonist at the mu-opioid receptor, and naloxone HCl dihydrate, an opioid receptor antagonist, at a ratio of 4:1 (ratio of free bases). It is intended for sublingual administration and is available in two dosage strengths, 2 mg buprenorphine with 0.5 mg naloxone and 8 mg buprenorphine with 2 mg naloxone. Each sublingual tablet also contains lactose, mannitol, cornstarch, povidone K30, citric acid, sodium citrate, FD&C Yellow No.6 color, magnesium stearate, acesulfame K sweetener and a lemon / lime flavor. Chemically, buprenorphine HCl is (2S)-2-[17-Cyclopropylmethyl-4,5α-epoxy-3-hydroxy-6-methoxy-6α,14ethano-14α-morphinan-7α-yl]-3,3-dimethylbutan-2-ol hydrochloride. It has the following chemical structure: Suboxone Sublingual tablets - Structural Formula Illustration Buprenorphine HCl has the molecular formula C29H41NO4 • HCl and the molecular weight is 504.10. It is a white or off-white crystalline powder, sparingly soluble in water, freely soluble in methanol, soluble in alcohol, and practically insoluble in cyclohexane. Chemically, naloxone HCl dihydrate is 17-Allyl-4, 5 α -epoxy-3, 14-dihydroxymorphinan-6-one hydrochloride dihydrate. It has the following chemical structure: Naloxone - Structural Formula Illustration Naloxone hydrochloride dihydrate has the molecular formula C19H21NO4 • HCl • 2H20 and the molecular weight is 399.87. It is a white to slightly off-white powder and is freely soluble in water, soluble in alcohol, and practically insoluble in toluene and ether.